Possible Increased Risk of Bone Fractures With Certain Antacid Drugs
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There is a possible increased risk of fractures of the hip, wrist, and spine if you take certain drugs for heartburn, acid reflux, or ulcers, warns the Food and Drug Administration (FDA).
The drugs belong to a class of medications called proton pump inhibitors (PPIs), which work by reducing the amount of acid in the stomach. They are available both as prescription and as over-the-counter (OTC) medications.
The prescription PPIs treat conditions such as gastroesophageal reflux disease (GERD), ulcers in the stomach and small intestine, and inflammation of the esophagus. The PPIs available over-the-counter are used to treat frequent heartburn.
The prescription PPIs are
The over-the-counter PPIs are
- Prilosec OTC (omeprazole)
- Zegerid OTC (omeprazole)
- Prevacid 24HR (lansoprazole)
Advice for Consumers
- Do not stop taking your PPI unless you are told to do so by your health care professional. PPIs are effective in treating a variety of gastrointestinal disorders.
- Be aware that an increased risk of fractures of the hip, wrist, and spine have been reported in some studies of people who use PPIs. The greatest increased risk for these fractures was seen in those who receive high doses of these medications or use them for a year or longer.
- Read and follow the directions on the “Drug Facts” label when considering the use of an over-the-counter PPI.
- Be aware that the over-the-counter PPIs should only be used as directed for 14 days for the treatment of frequent heartburn. If your heartburn continues, talk to your health care professional. No more than three 14-day treatment courses should be used in one year.
- Talk to your health care professional about any concerns you may have about using PPIs.
- Report any side effects from the use of PPIs to FDA’s MedWatch Adverse Event Reporting Program either online, by regular mail, by fax, or by phone.
FDA has reviewed seven published studies, six of which reported an increased risk of fractures of the hip, wrist, and spine with the use of PPIs. Based on the available data, it is not clear at this time if the use of PPIs is the cause of the increased risk of fractures seen in some studies. FDA is working with the manufacturers of PPIs to further study this possible risk.
Most of the studies evaluated individuals 50 years of age or older, and the increased risk of fracture was seen mainly in this age group.
As a precaution, FDA is revising the labels for both the prescription and the over-the-counter PPIs to include new safety information about the possible increased risk of fractures of the hip, wrist, and spine with the use of these medications.
This article appears on FDA’s Consumer Updates page, which features the latest on all FDA-regulated products.
Date Posted: May 25, 2010
As you might expect, I constantly scour medical publications, articles and research studies to see the latest and greatest treatment for various sicknesses, with an emphasis on digestive problems.
This helps me understand the mindset and past experiences of someone who comes to me and says something like, “I get terrible gas and bloating every time I eat. I’ve been to 5 doctors, had tons of tests and all they want to do is give me more medications that aren’t helping me. Can you PLEASE help?”
I was just reading an article about constipation written by a gastroenterologist that literally made me laugh out loud.
One of the causes of constipation he mentioned was overuse of laxatives. Then three paragraphs later, he suggests laxatives as a solution to constipation!
Make up your mind, will you?
Another constipation cause he mentioned was putting off or delaying the urge to have a bowel movement.
I don’t know about you, but when Nature calls, I answer, and so do most adults. The people typically known for deliberately “holding it” are kids because they’re too busy playing to take time out to go or they’re resisting toilet training.
And here was the funniest one of all: He said that older age was a cause of constipation.
Oh, OK. So once you’re, say, 70 or older, you can count on having enough time to read War and Peace whenever you’re on the throne?
Maybe he got his degree from Atsamatta U.
Now, the article did make a few suggestions that were in the right direction, but they were the same old, tired remedies for constipation that you’ve heard a million times: Increase water intake, eat more fiber and exercise.
And if those remedies are really the true key to eliminating constipation, then why are there STILL so many blocked up people who drink water, eat fiber and exercise??
I’ll tell you why.
The most common cause of constipation
Because THE MOST COMMON cause of constipation is one that you’ll likely never hear from a doctor, dietitian or any health-related article (except this email, of course!).
It’s poor digestion… food that goes in OK, but doesn’t get broken down and digested properly.
You see, when your foods are completely broken down and digested like they should be, your wastes slide out the back door nice and easy–with no grunting, straining or rabbit turds.
But when your digestion is poor, your wastes are hard, sticky and mucus covered. They can adhere to your colon wall to the point where you feel like you need a sandblaster to get them off.
The additional price of constipation
Not only does constipation cause the typical gas, bloating and hemorrhoids, but you also get a massive buildup of toxins in your colon that can get absorbed into your bloodstream and wreak havoc everywhere in your body.
In addition to the common problems above, constipation can also lead to:
Malabsorption of nutrients
And the toxins from your gut that are now sailing through your veins put a tremendous stress on your liver to try and filter them out.
And last but not least, those wastes lining your colon wall create an environment for harmful bacteria overgrowth. This will weaken your immune system and make you susceptible to every bug or virus in the air.
The real key to ending constipation
The key to ending constipation is to make your digestion as complete and thorough as possible.
There are 3 things you can do to make this happen:
Eating easy to digest meals with a good balance of foods that are alkaline and natural sources of fiber makes your stomach’s job easier (and helps curb conditions like acid reflux), but that’s not all.
When your foods are digested properly, your wastes can glide through the intestines easily. So bye-bye constipation.
In my health systems, Great Taste No Pain and for gluten-sensitive people, Great Taste No Gluten
I show you how to put together meals that are not only delicious, but are MUCH easier for your body to digest. This results in things “moving along” like they should.
One of the most common things I hear from my clients is that they’re thrilled to be having daily BMs…when many of them haven’t been “regular” for years, with some having fewer than one bowel movement every week or two or even less.
Can you imagine?
2) Balance your intestinal flora
Your beneficial bacteria help break down certain foods and fiber, so having a proper population of them is essential for thorough digestion and avoiding constipation.
Trouble is, thanks to our typical diets and toxin buildup from constipation, many people are walking around with harmful bacteria overgrowth.
Super Shield multi-strain probiotic formula can help turn that around for you.
Super Shield can help you achieve and maintain the critical balance of at least 85% beneficial bacteria and 15% or less harmful bacteria. This is so crucial to digestive health and a strong immune system.
Super Shield’s 13 strains of pharmaceutical-grade probiotic bacteria will crowd out the “bad guys” in your gut, enhance your digestion and get things moving along a whole lot easier for you.
3) Give your enzymes a boost
The reason constipation is seen in older age people even when they’ve never had a digestive issue in their life is because, hard to digest foods have used up their body’s ability to produce enzymes.
And now they’re S.O.L.
You see, your body uses up a tremendous amount of enzymes trying to break down today’s most popular processed foods. And it can only produce so many enzymes. Once they’re gone, they’re gone!
Inadequate enzymes = poor digestion = constipation
Digestizol Max digestive enzymes can be a tremendous help for people with low enzymes.
Digestizol Max’s blend of 14 plant-derived enzymes will give your body the help it needs to break down proteins, fats, carbs, fiber and dairy. Whatever you eat, Digestizol Max has you covered!
Don’t waste one more minute relying on constipation remedies that don’t work or living your life on laxatives.
Say goodbye to grunting for good and hello to comfortable, regular bowel movements.
See what a difference it can make to attack constipation at its root cause.
To your health,
How many of you had a hairy baby? Did you have heartburn during pregnancy?
I read that when you have heartburn during pregnancy it means you are more likely to have a hairy baby. With my first I did not have heart burn and he barely had any hair, with this one I have horrible heartburn and he is hairy 🙂 Does this work for you? What do you think?
Yes with my first child i had a little heartburn & he had some hair & with my second child i had worse heartburn & he had lots more hair
What can you do if You have Heartburn During Pregnancy?
I have termenous heartburn during my pregnancy. I am 6.5 months pregnant and my heartburn is getting the best of me. Is there anything that anyone recommends that can ease my heartburn. I would be truly grateful if I can get some advice.
Hiya! Dee! My advise to you hon, is start taking yoghurt on a daily basis. 500mls in total! 250mls after breakfast, and 250mls before bedtime, there are lots of brands out there including flavoured. Your problem is too much acid entering your gut.Take it with a desert spoon but slowly. Avoid oranges, bacon, and cut down on bread and cakes. Hope you will find relief from discomfort and look forward to your forthcoming motherhood. > JK <
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1) Get enough sleep
Nothing can wipe out your immune system faster than inadequate sleep. Life goes on without SNL, Jay Leno or Seinfeld reruns. Turn off the TV and get some decent rest.
2) Avoid fast food, processed food, sugars, refined carbs and excessive alcohol consumption.
All of these feed the harmful bacteria in your gut, which can then crowd out your friendly flora and greatly hamper your immune function.
3) Limit antibiotic use
They can be life-savers, but antibiotics can also obliterate your immune system because they destroy your good bacteria as well as the illness-causing bacteria.
If you must take them, be sure to help counteract their harmful effects with a good probiotic supplement (more on that below).
Stress causes your body’s protective mucosal barrier to become less effective at defending against unfriendly bacteria and dangerous pathogens. That’s why many people get sick when under stress — because their bodies literally can’t fight off illness as well.
There are many ways to help de-stress: Meditation, exercise, counseling, deep breathing and seminars, to name a few. Choose one or more and feel the burdens of each day melt away.
5) Take a top-shelf multi-strain probiotic
One medical-grade bacteria strains, Lactobacillus Rhamnosus, has been shown to stimulate antibody production and enhance phagocytosis (one of your body’s weapons for destroying dangerous invaders).
In addition, Bifidobacteria Lactis, has high adhesion to human mucus. That means it will stick to your colon wall to keep it strong and protective, which helps keep wastes and dangerous toxins and bacteria from leaking out into the bloodstream and making you SICK. This is especially good for you milk drinkers and cheese-a-holics.
6) Make sure you have adequate B12
In addition to helping your body generate energy and keeping your thinking sharp and clear, vitamin B12 is also essential for strong immune function.
B12 is crucial for the formation of red and white blood cells, which help boost your immune function.
Problem is, 1 out of 4 people are deficient in B12. Especially vulnerable are people over age 50, people who take acid reducers, vegetarians and people with Crohn’s, colitis or IBS.
But even if you eat foods that are rich in B12 or take supplements, B12 is not easily absorbed through the GI tract…so chances are good you’re getting far less than what you need.
The easiest way to make sure you have enough is to supplement with a highly absorbable form of B12.
Like Hydroxaden 2.5.
Hydroxaden 2.5 is an easy to use form of B12. Just 5 little sprays under your tongue gives you a full 2.5 mg of B12, comprised of two of the best forms–hydroxocobalamin (which raises your B12 level faster than other forms) and adenosylcobalamin (the form of B12 most used by your brain).
And it’s more absorbable than any other form of B12…period.
Due to it’s nano particles, no other form of B12 absorbs faster or more completely.
Your immune system is a primary key to your health and a normal life.
It is your key to helping to fight off colds, flu, infections and even deadly diseases 12 months a year.
Do as much as you can to keep your immune function strong, and you can reap the rewards of fewer or less severe illnesses and quite possibly, avoidance of more dangerous diseases.